Polynucleotides

Polynucleotides (PN) are long chains of nucleotides, which are the building blocks of DNA and RNA. When used in skincare, these molecules are typically derived from marine sources (such as salmon DNA) and are used to promote cell repair and regeneration in the skin. Polynucleotides, like DNA and RNA, can interact with the skin cells to promote healing, improve skin texture, and stimulate the production of essential proteins like collagen and elastin.

Benefits of Polynucleotides for Skin

Chemical peels work by applying a chemical solution (usually containing acids) to the skin, which causes the top layers of skin to peel off. Depending on the type of peel and its depth, the skin’s healing process encourages the growth of healthier skin cells.There are three main types of chemical peels, categorized by how deeply they penetrate the skin:

  1. Skin Repair: Polynucleotides can help stimulate the repair of damaged skin cells. They support cell regeneration and can be especially beneficial for those with skin conditions like scars, acne, or post-surgery recovery.

  2. Collagen and Elastin Production: By stimulating fibroblast cells, polynucleotides encourage the production of collagen and elastin, which are key proteins responsible for skin's firmness, elasticity, and youthful appearance.

  3. Hydration: Polynucleotides attract and retain moisture in the skin, leading to improved hydration. This can make the skin appear plumper and more radiant.

  4. Anti-inflammatory: Polynucleotides have anti-inflammatory properties, which can help reduce redness, irritation, and swelling in the skin. This makes them useful in treating inflammatory skin conditions or post-treatment inflammation.

  5. Treatment for Dark Circles: The application of polynucleotides can improve blood circulation around the delicate under-eye area, helping to reduce dark circles. They may also help strengthen the thin skin in this area.

  6. Microcirculation: Polynucleotides can help improve microcirculation, which refers to blood flow in the smaller blood vessels of the skin. Enhanced circulation leads to better oxygenation and nutrient delivery to skin cells, promoting healthier skin.

  7. Reduction of Wrinkles: By stimulating collagen and elastin production and improving skin hydration, polynucleotides can help smooth lines and wrinkles, giving the skin a firmer and more youthful appearance.

How Are Polynucleotides Used in Skin Treatments?

Polynucleotides are typically administered through injections. The two main methods of delivery are:

  • Needles: Small injections are made directly into the skin layers.

  • Cannulas: A blunt-ended tube may be used to deliver polynucleotides to deeper layers of skin, often for more controlled application and to minimize bruising.

Treatment Results and Timeline

  • Visible Results: While the full effects of polynucleotide treatments might take up to three months to become visible, patients often notice improvements in hydration, skin texture, and elasticity in the weeks following treatment.

  • Long-Term Benefits: Consistent treatments may help maintain skin health by continuously stimulating repair, collagen production, and hydration.

Polynucleotides have become a sought-after tool in skincare, particularly in aesthetic dermatology, for their ability to regenerate skin, reduce wrinkles, and improve skin tone and texture. They harness the regenerative power of DNA and RNA at the cellular level to heal and rejuvenate the skin, making them effective for a variety of skin concerns.

After receiving a polynucleotide treatment (such as an injection of polynucleotides for skin rejuvenation or repair), proper aftercare is essential to ensure optimal results and minimize potential side effects. Below are some general aftercare guidelines that are typically recommended following a polynucleotide skin treatment:

  • Avoid Touching or Massaging the Treated Area

  • Avoid Heat and Sun Exposure

  • Stay Away from Strenuous Exercise

  • Avoid Alcohol and Smoking

  • Follow Your Skincare Routine Carefully

  • Hydrate Your Skin

  • Be Patient with the Results